HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
5-fluoro-1-methyl-1H-indole-3-carbaldehyde → 5-fluoro-1-methyl-3-(methylaminomethyl)-1H-indole
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 5-fluoro-1-methyl-1H-indole-3-carbaldehyde | HCID 1382009 | — |
| Edukt | Methyl 2-((5-bromopyridin-2-yl)amino)acetate | HCID 22139049 | — |
| Produkt | 5-fluoro-1-methyl-3-(methylaminomethyl)-1H-indole | HCID 22139018 | 35% |
Reaktionsschritte
According to the procedure of Preparation 11 (c), except substituting 5-fluoro-1-methyl-1H-indole-3-carboxaldehyde (0.3 g, 1.69 mmole) for the 1,3 dimethyl-1H-2-carboxaldehyde, the title compound (0.11 g, 35%) was prepared as a viscous oil: MS (ES) m/e 193 (M+H)+.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07741339B2 |
| Quelldatensatz | uspto-grants-2010_06 |
| ORD ID | ord-34a62e740bff46038c49b2384251f032 |
| Quellennotiz | uspto-grants-2010_06 |