HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
3-Methoxy-2-methyl-3-oxopropanoic acid → N-[4-(3-Fluoro-benzyloxy)-phenyl]-2-methyl-malonamic Acid Methyl Ester
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 3-Methoxy-2-methyl-3-oxopropanoic acid | HCID 300693 | — |
| Edukt | 4-(3-Fluoro-benzyloxy)-phenylamine | HCID 16775314 | — |
| Lösungsmittel | Dichloromethane methanol | HCID 21226129 | — |
| Produkt | N-[4-(3-Fluoro-benzyloxy)-phenyl]-2-methyl-malonamic Acid Methyl Ester | HCID 69008808 | — |
Reaktionsschritte
The title compound is prepared in analogy to example 2, starting from 4-(3-fluoro-benzyloxy)-phenylamine (as prepared in example 1b) and 2-methyl-malonic acid monomethyl ester (Nader et al., Chem. Ber. 1986, 119, 1196). Yield after flash-chromatography with dichloromethane/methanol 98:2: 40%. Colorless solid. Mp=119° C.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07053245B2 |
| Quelldatensatz | uspto-grants-2006_05 |
| ORD ID | ord-bed5bd75eb954cd09d50d747cf6c9177 |
| Quellennotiz | uspto-grants-2006_05 |