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HRID 1840907Erstellt: 24. Oktober 2026

Quinuclidine, 3-amino-, dihydrochloride → (Rs)-n-(1-azabicyclo[2.2.2]oct-3-yl)[e-3-(2-trifluoromethylphenyl)propenamide]

https://huagongshe.com/de/reaction/1840907

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
EduktQuinuclidine, 3-amino-, dihydrochlorideHCID 197853—
Edukt2-(Trifluoromethyl)cinnamic acid, (E)-HCID 719625—
Produkt(Rs)-n-(1-azabicyclo[2.2.2]oct-3-yl)[e-3-(2-trifluoromethylphenyl)propenamide]HCID 9945116—

Reaktionsschritte

Prepared as a free base by a method analogous to that described in Example 1 from racemic 1-azabicyclo[2.2.2]oct-3-ylamine dihydrochloride and E-3-(2-trifluoromethylphenyl)propenoic acid; MS (ES+) 325 (MH+).

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS06683090B1
Quelldatensatzuspto-grants-2004_01
ORD IDord-20d1366df0bf4007a0db4970cb2f3893
Quellennotizuspto-grants-2004_01