HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
2H-Pyran-3(4H)-one, dihydro- → 3-(3,4-Difluorophenyl)-1,4,5,7-tetrahydropyrano[3,4-c]pyrazole
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 2H-Pyran-3(4H)-one, dihydro- | HCID 90109 | — |
| Edukt | tert-butyl 3-(3,4-difluorophenyl)-6,7-dihydro-1H-pyrazolo[4,3-c]pyridine-5(4H)-carboxylate | HCID 59345327 | — |
| Produkt | 3-(3,4-Difluorophenyl)-1,4,5,7-tetrahydropyrano[3,4-c]pyrazole | HCID 59345352 | — |
Reaktionsschritte
Intermediate 16B was prepared according to the procedure for the synthesis of intermediate 15 by replacing 1-Boc-4-piperidone with dihydro-2H-pyran-3(4H)-one LCMS (+ESI) m/z=236 [M+H]+. 1H NMR (CDCl3) δ 7.37-7.41 (m, 1H), 7.29-7.32 (m, 1H) 7.17-7.24 (m, 1H), 4.76 (s, 2H), 3.95 (t, J=5.5 Hz, 2H), 2.84 (t, J=5.5 Hz, 2H).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07741350B1 |
| Quelldatensatz | uspto-grants-2010_06 |
| ORD ID | ord-6e0b9274922e4fb6a2c5c20b9494402a |
| Quellennotiz | uspto-grants-2010_06 |