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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 1850459Erstellt: 23. Oktober 2026

1-(p-Tolyl)piperazine → 1-(7-Ethoxy-2,4,6-trimethyl-2,3-dihydro-1-benzofuran-5-yl)-4-(4-methylphenyl)piperazine

https://huagongshe.com/de/reaction/1850459

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
Edukt1-(p-Tolyl)piperazineHCID 83113—
EduktHCID 66759168HCID 66759168—
Produkt1-(7-Ethoxy-2,4,6-trimethyl-2,3-dihydro-1-benzofuran-5-yl)-4-(4-methylphenyl)piperazineHCID 5948504543%

Reaktionsschritte

By using 5-bromo-7-ethoxy-2,4,6-trimethyl-2,3-dihydro-1-benzofuran (570 mg, 2.0 mmol) synthesized in Reference example 84 and 1-(4-methylphenyl)piperazine (704 mg, 4.0 mmol), the reaction was carried out in the same manner as Example 21 to synthesize the title compound 327 mg (yield 43%).

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS08957069B2
Quelldatensatzuspto-grants-2015_02
ORD IDord-5169d4738da04a5d94fb7c7ac228ba09
Quellennotizuspto-grants-2015_02