HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
1-(p-Tolyl)piperazine → 1-(7-Ethoxy-2,4,6-trimethyl-2,3-dihydro-1-benzofuran-5-yl)-4-(4-methylphenyl)piperazine
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 1-(p-Tolyl)piperazine | HCID 83113 | — |
| Edukt | HCID 66759168 | HCID 66759168 | — |
| Produkt | 1-(7-Ethoxy-2,4,6-trimethyl-2,3-dihydro-1-benzofuran-5-yl)-4-(4-methylphenyl)piperazine | HCID 59485045 | 43% |
Reaktionsschritte
By using 5-bromo-7-ethoxy-2,4,6-trimethyl-2,3-dihydro-1-benzofuran (570 mg, 2.0 mmol) synthesized in Reference example 84 and 1-(4-methylphenyl)piperazine (704 mg, 4.0 mmol), the reaction was carried out in the same manner as Example 21 to synthesize the title compound 327 mg (yield 43%).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08957069B2 |
| Quelldatensatz | uspto-grants-2015_02 |
| ORD ID | ord-5169d4738da04a5d94fb7c7ac228ba09 |
| Quellennotiz | uspto-grants-2015_02 |