N-(2-Cyanophenyl)piperazine → 1-[(6-Fluoro-3-methoxyquinoxalin-2-yl)aminocarbonyl]-4-(2-cyanophenyl)piperazine

Beteiligte Stoffe

Reaktionsschritte

Ethyl N-(6-fluoro-3-methoxyquinoxalin-2-yl)carbamate and 1-(2-cyanophenyl)piperazine were reacted by the same way with the example 85 to obtain the titled compound (yield, 88%). 1H NMR (200 MHz, CDCl3): δ 3.31 (s, 4H), 3.84 (s, 4H), 4.15 (s, 3H), 7.03-7.10 (m, 2H), 7.25-7.61 (m, 5H), 7.82 (dd, J=8.7 and 5.7 Hz, 1H).

Herkunft & Nachweise