HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Benzene → 2-[2-(4-Methoxycarbonylmethylphenoxy)-1-methylethyl]amino-1-(4-chlorophenyl)ethanol
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Benzene | HCID 241 | — |
| Edukt | 2-Amino-1-(4-chlorophenyl)ethan-1-ol | HCID 412434 | — |
| Edukt | Sodium cyanoborohydride | HCID 5003444 | — |
| Edukt | Methyl 4-(2-oxopropoxy)phenylacetate | HCID 21832178 | — |
| Lösungsmittel | Methanol | HCID 887 | — |
| Produkt | 2-[2-(4-Methoxycarbonylmethylphenoxy)-1-methylethyl]amino-1-(4-chlorophenyl)ethanol | HCID 53655583 | 35% |
Reaktionsschritte
Following a procedure similar to that described in Example 12, but using 2 g of 2-amino-1-(4-chlorophenyl)ethanol (prepared as described in Preparation 12), 3.11 g of methyl 4-(2-oxopropoxy)phenylacetate (prepared as described in Preparation 3), 60 ml of benzene, 50 ml of absolute methanol and 2.7 g of sodium cyanoborohydride, 1.54 g of the title compound were obtained as crystals, melting at 78°-79° C.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US05576340 |
| Quelldatensatz | uspto-grants-1996_11 |
| ORD ID | ord-367eb7baf1c648fcb87f1f0de8bac772 |
| Quellennotiz | uspto-grants-1996_11 |