HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
N-(2-methoxyethyl)cyclohexanamine → N-[4-(aminosulfonyl)-2-methylphenyl]-6-[cyclohexyl(2-methoxyethyl)amino]pyrimidine-4-carboxamide
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | N-(2-methoxyethyl)cyclohexanamine | HCID 12687399 | — |
| Edukt | 6-Chloro-pyrimidine-4-carboxylic acid (2-methyl-4-sulfamoyl-phenyl)amide | HCID 59447056 | — |
| Produkt | N-[4-(aminosulfonyl)-2-methylphenyl]-6-[cyclohexyl(2-methoxyethyl)amino]pyrimidine-4-carboxamide | HCID 25182783 | 82% |
Reaktionsschritte
Following the general method as outlined in Example 20, starting from 6-chloro-pyrimidine-4-carboxylic acid (2-methyl-4-sulfamoyl-phenyl)-amide (Intermediate 17) and cyclohexyl-(2-methoxy-ethyl)-amine (Intermediate 26), the title compound was obtained as a white solid in 82% yield.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08399448B2 |
| Quelldatensatz | uspto-grants-2013_03 |
| ORD ID | ord-dc7140b8799e4b6ba0bc897e288a2634 |
| Quellennotiz | uspto-grants-2013_03 |