HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
2-chloro-N-(2-methoxyethyl)acetamide → 6-{2-{Ethyl {4-[2-(2-methoxyethylamino)ethoxy]benzyl}amino}-4-methoxyphenyl}-5,6,7,8-tetrahydronaphthalen-2-ol
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 2-chloro-N-(2-methoxyethyl)acetamide | HCID 2386048 | — |
| Edukt | Pivalic acid 6-{2-[ethyl(4-hydroxybenzoyl)amino]-4-methoxyphenyl}-5,6,7,8-tetrahydronaphthalen-2-yl ester | HCID 57934562 | — |
| Produkt | 6-{2-{Ethyl {4-[2-(2-methoxyethylamino)ethoxy]benzyl}amino}-4-methoxyphenyl}-5,6,7,8-tetrahydronaphthalen-2-ol | HCID 58023083 | 13,9% |
Reaktionsschritte
Synthesized from pivalic acid 6-{2-[ethyl(4-hydroxybenzoyl)amino]-4-methoxyphenyl}-5,6,7,8-tetrahydronaphthalen-2-yl ester (25 mg) and 2-chloro-N-(2-methoxyethyl)acetamide (14 mg) according to an analogous synthetic method to Example 567 and purified by LC-MS, the title compound (3.5 mg) was obtained.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08399520B2 |
| Quelldatensatz | uspto-grants-2013_03 |
| ORD ID | ord-f8dd7c0536fa41d8b63252ef0bc2bf73 |
| Quellennotiz | uspto-grants-2013_03 |