Zurück
HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 1986246Erstellt: 24. Oktober 2026

1-(3-Aminopropyl)-4-methylpiperazine → 2-{5-Methyl-2-[3-(4-methyl-piperazin-1-yl)-propylamino]-pyrimidin-4-yl}-benzo[b]thiophen-4-ol

https://huagongshe.com/de/reaction/1986246

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
Edukt1-(3-Aminopropyl)-4-methylpiperazineHCID 78328—
Edukt[4-(Benzo[b]thiophen-2-yl)-pyrimidin-2-yl]-[3-(4-methylpiperazin-1-yl)-propyl]-amine tri-hydrochlorideHCID 68855962—
Edukt2-(2-Chloro-5-methylpyrimidin-4-yl)benzo[b]thiophen-4-olHCID 136343969—
Produkt2-{5-Methyl-2-[3-(4-methyl-piperazin-1-yl)-propylamino]-pyrimidin-4-yl}-benzo[b]thiophen-4-olHCID 136343970—

Reaktionsschritte

Using the method of [4-(benzo[b]thiophen-2-yl)-pyrimidin-2-yl]-[3-(4-methylpiperazin-1-yl)-propyl]-amine tri-hydrochloride, the title compound is prepared from 2-(2-chloro-5-methylpyrimidin-4-yl)benzo[b]thiophen-4-ol and 1-(3-aminopropyl)-4-methylpiperazine and isolated as a solid. ES+(m/z) 398 [M+H].

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS07547691B2
Quelldatensatzuspto-grants-2009_06
ORD IDord-a9dfc7bd51974ca6ae67844a58dcff0b
Quellennotizuspto-grants-2009_06