2-Chloropyridine-4-boronic acid → [1-(2-Chloro-pyridin-4-yl)-5-(4-isopropyl-piperazine-1-carbonyl)-1H-indol-2-yl]-[4-(propane-2-sulfonyl)-piperazin-1-yl]-methanone

Beteiligte Stoffe

Reaktionsschritte

The title compound was synthesized in analogy to example 5, after stirring for 3.5 days at 35° C., from [5-(4-isopropyl-piperazine-1-carbonyl)-1H-indol-2-yl]-[4-(propane-2-sulfonyl)-piperazin-1-yl]-methanone (example 15) and 2-chloropyridine-4-boronic acid to afford the desired product as a light-brown foam (41%). MS (ISP): 601.4 (M+H)+.

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