Sodium Hydroxide → HCID 22724875, Verbindung

HRID 2086562

Reaktionsgleichung

Reaktionsgleichung von HRID 2086562
C[O:2][C:3]([C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][C:6]=1[NH:11][C:12](=[O:24])/[CH:13]=[CH:14]/[C:15]1[CH:20]=[CH:19][CH:18]=[C:17]([N+:21]([O-:23])=[O:22])[CH:16]=1)=[O:4].[OH-].[Na+]>CO>[C:3]([C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][C:6]=1[NH:11][C:12](=[O:24])/[CH:13]=[CH:14]/[C:15]1[CH:20]=[CH:19][CH:18]=[C:17]([N+:21]([O-:23])=[O:22])[CH:16]=1)([OH:4])=[O:2]

Komponenten

4

Edukt 2

HCID 14798Sodium HydroxideHCID 692365methyl 2-[(2E)-3-(3-nitrophenyl)prop-2-enoylamino]benzoate

Produkt 1

HCID 22724875HCID 22724875, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 887MethanolLösungsmittel

Versuchsvorschrift

500 mg (1.53 mmol) of trans-3-nitrocinnamic acid-N-(2-methoxycarbonyl-phenyl)-amide are stirred into a mixture of 20 ml of methanol and 8 ml of 2N sodium hydroxide solution for two hours at 50° C. Then the methanol is distilled off in vacuo, the residue is diluted with about 150 ml of water and adjusted to about pH 2.5 with stirring. The product which is then precipitated is suction filtered, washed with about 10 ml of water and dried.

Aufarbeitung

  1. distillationThen the methanol is distilled off in vacuo
  2. additionthe residue is diluted with about 150 ml of water
  3. customThe product which is then precipitated
  4. filtrationfiltered
  5. washwashed with about 10 ml of water
  6. customdried

Quellen und Nachweise

ORD-Eintrag
ord-6ed9cdad5340498287da76fd7f799bf4
Quelldatensatz
uspto-grants-2004_04
Patentnummer
US06727250B2

Verknüpfte Notizen

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