HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Furan-2-acetic acid → N-(4'-{[(Cyclopropylmethyl)amino]carbonyl)6-methyl-1,1'-biphenyl-3-yl)-2-(fur-2-yl)acetamide
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Furan-2-acetic acid | HCID 75974 | — |
| Edukt | 5'-amino-N-(cyclopropylmethyl)-2'-methyl-1,1'-biphenyl-4-carboxamide | HCID 11300488 | — |
| Produkt | N-(4'-{[(Cyclopropylmethyl)amino]carbonyl)6-methyl-1,1'-biphenyl-3-yl)-2-(fur-2-yl)acetamide | HCID 69200721 | — |
Reaktionsschritte
N-(4′-{[(Cyclopropylmethyl)amino]carbonyl}6-methyl -1,1′-biphenyl-3-yl)-2-(fur-2-yl)acetamide was prepared from 5′-amino-N-(cyclopropylmethyl)-2′-methyl-1,1′-biphenyl-4- carboxamide and fur-2-ylacetic acid using method D. NMR; δH [2H6]—DMSO 10.17,(1H, s), 8.61,(1H, t), 7.91,(2H, d), 7.55,(1H, m), 7.50-7.48,(2H, m), 7.40,(2H, d), 7.23,(1H, d), 6.38,(1H, m), 6.25,(1H, d), 3.70,(2H, s), 3.16,(2H, t), 2.16,(3H, s), 1.04,(2H, m), 0.42,(2H, m). LCMS: retention time 3.26 min, MH+389.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07432289B2 |
| Quelldatensatz | uspto-grants-2008_10 |
| ORD ID | ord-5fe580bfd24741fba4ffe7a35292f54a |
| Quellennotiz | uspto-grants-2008_10 |