m-Chloroperbenzoic acid → N-(3-chloro-phenyl)-4-(N-oxido4-pyridyl)-2-pyrimidineamine

Beteiligte Stoffe

Rolle	Name	HCID	Einwaage
Edukt	m-Chloroperbenzoic acid	HCID 70297	—
Edukt	2-pyrimidinamine, N-(3-chlorophenyl)-4-(4-pyridinyl)-	HCID 644214	—
Lösungsmittel	Dichloromethane	HCID 6344	—
Produkt	N-(3-chloro-phenyl)-4-(N-oxido4-pyridyl)-2-pyrimidineamine	HCID 19689585	—

Reaktionsschritte

10 g (35.4 mmol) of N-(3-chloro-phenyl)-4-(4-pyridyl)-2-pyrimidineamine and 11.1 g (35.4 mmol) of m-chloroperbenzoic acid are stirred for 5 h at RT in 500 ml of methylene chloride. Concentration and crystallisation (acetic acid) of the residue give N-(3-chloro-phenyl)-4-(N-oxido4-pyridyl)-2-pyrimidineamine; m.p. 274°-275°, Rf =0.6 (methylene chloride:methanol=9:1).

Herkunft & Nachweise

DOI	10.6084/m9.figshare.5104873.v1
Patentnummer	US05728708
Quelldatensatz	uspto-grants-1998_03
ORD ID	ord-a39fc3b67bbd45ff88d29b84e47f577f
Quellennotiz	uspto-grants-1998_03