HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Hydrochloric Acid → 4-Phenylpiperidine-4-carboxylic acid, compound with toluene-p-sulphonic acid
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Hydrochloric Acid | HCID 313 | — |
| Edukt | 1-((Tert-butoxy)carbonyl)-4-phenylpiperidine-4-carboxylic acid | HCID 736917 | — |
| Lösungsmittel | 1,4-Dioxane | HCID 31275 | — |
| Produkt | 4-Phenylpiperidine-4-carboxylic acid, compound with toluene-p-sulphonic acid | HCID 19259 | 109,3% |
Reaktionsschritte
1-(tert-Butoxycarbonyl)-4-phenylpiperidine-4-carboxylic acid (1.0 g, 3.3 mmol) was treated with 4 N HCl in dioxane (20 mL) for 2 hours at room temperature. The product was isolated by filtration to provide the title compound (0.74 g, 93%) as a white solid. MS (ES+) [M+H]+=206.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08193202B2 |
| Quelldatensatz | uspto-grants-2012_06 |
| ORD ID | ord-1df7985a55a04ddfa276f21ffbc22a18 |
| Quellennotiz | uspto-grants-2012_06 |