Hydrochloric Acid → N-(3-tert-butylphenyl)-4-methylpiperidine-4-carboxamide

Beteiligte Stoffe

Reaktionsschritte

tert-Butyl 4-(3-tert-butylphenylcarbamoyl)-4-methylpiperidine-1-carboxylate from step A (0.4 g, 1.07 mmol) was treated with HCl (4.0 N in dioxane, 1.3 mL, 5.34 mmol) in methanol (5.0 mL) at 50° C. for 30 minutes. The mixture was concentrated to give the title compound as the hydrochloride salt in quantitative yield. MS (ES+) [M+H]+=275.

Herkunft & Nachweise