HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Methyl iodide → N,N-diethyl 2-chloro-6-methylbenzamide
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Methyl iodide | HCID 6328 | — |
| Edukt | 2-Chloro-N,N-diethylbenzamide | HCID 82566 | — |
| Produkt | N,N-diethyl 2-chloro-6-methylbenzamide | HCID 18630133 | 92% |
Reaktionsschritte
The compound from example e (1.0 eq) and MeI (3.0 eq) were combined according to Method A. The crude product was purified by HPLC with 1:4 EtOAc/hexanes to give 5.2 g of N,N-diethyl 2-chloro-6-methylbenzamide as a yellow solid, a 92% yield. m.p. 48°-49° C.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US06410558B1 |
| Quelldatensatz | uspto-grants-2002_06 |
| ORD ID | ord-6e4686cee83448fdaf5bb2bce7a792cc |
| Quellennotiz | uspto-grants-2002_06 |