HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Methyl 5-bromopyridine-3-carboxylate → Methyl 5-(4-(trifluoromethyl)phenyl)nicotinate
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Methyl 5-bromopyridine-3-carboxylate | HCID 699336 | — |
| Edukt | 4-(Trifluoromethyl)phenylboronic acid | HCID 2734389 | — |
| Produkt | Methyl 5-(4-(trifluoromethyl)phenyl)nicotinate | HCID 20099855 | — |
Reaktionsschritte
According to General Method 3A, 28 g (132 mmol) of methyl 5-bromonicotinate and 30 g (158 mmol, 1.2 eq.) of 4-trifluoromethylphenylboronic acid were reacted. Yield: 32 g (85% of theory)
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08202862B2 |
| Quelldatensatz | uspto-grants-2012_06 |
| ORD ID | ord-bdf78bc2be8049e0b993b65f6f54d99e |
| Quellennotiz | uspto-grants-2012_06 |