HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Tributylstannane → 2-Ethoxycarbonylimino-3-(3-trifluoromethylphenyl)thiazoline
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Tributylstannane | HCID 5948 | — |
| Edukt | Benzoyl Peroxide | HCID 7187 | — |
| Edukt | 2-Ethoxycarbonylimino-3-(3-trifluoromethylpheny)-5-bromothiazoline | HCID 54096993 | — |
| Lösungsmittel | Tetrahydrofuran | HCID 8028 | — |
| Produkt | 2-Ethoxycarbonylimino-3-(3-trifluoromethylphenyl)thiazoline | HCID 54352089 | 75,8% |
Reaktionsschritte
A solution of 2-ethoxycarbonylimino-3-(3-trifluoromethylphenyl)-5-bromothiazoline (4.7 g), tributyltin hydride (6.9 g) and a catalytic amount of benzoyl peroxide in tetrahydrofuran (100 ml) was refluxed for 10 hours. The solvent was removed by distillation, and the residue was washed with hexane. Recrystallization from a mixture of hexane and ethanol gave 2.85 g of 2-ethoxycarbonylimino-3-(3-trifluoromethylphenyl) thiazoline (Compound (xii)).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US05426188 |
| Quelldatensatz | uspto-grants-1995_06 |
| ORD ID | ord-c6888d67ee3542789f12cd043e1c654d |
| Quellennotiz | uspto-grants-1995_06 |