2-(Trifluoromethyl)benzoyl chloride → ethyl N-(o-trifluoromethyl-benzoyl)-2-fluoro-4-chlorobenzimidate

HRID 2232449

Reaktionsgleichung

Reaktionsgleichung von HRID 2232449
[Cl:1][C:2]1[CH:12]=[CH:11][C:5]([C:6](=[NH:10])[O:7][CH2:8][CH3:9])=[C:4]([F:13])[CH:3]=1.[F:14][C:15]([F:26])([F:25])[C:16]1[CH:24]=[CH:23][CH:22]=[CH:21][C:17]=1[C:18](Cl)=[O:19]>>[F:14][C:15]([F:25])([F:26])[C:16]1[CH:24]=[CH:23][CH:22]=[CH:21][C:17]=1[C:18]([N:10]=[C:6]([O:7][CH2:8][CH3:9])[C:5]1[CH:11]=[CH:12][C:2]([Cl:1])=[CH:3][C:4]=1[F:13])=[O:19]

Komponenten

3

Edukt 2

HCID 675612-(Trifluoromethyl)benzoyl chlorideHCID 19373098Ethyl 4-chloro-2-fluorobenzimidate

Produkt 1

HCID 21283811ethyl N-(o-trifluoromethyl-benzoyl)-2-fluoro-4-chlorobenzimidate

Versuchsvorschrift

starting from ethyl 4-chloro-2-fluorobenzimidate and o-trifluoromethyl-benzoyl chloride there is obtained ethyl N-(o-trifluoromethyl-benzoyl)-2-fluoro-4-chlorobenzimidate and therefrom with methylhydrazine there is obtained 3-(4-chloro-2-fluorophenyl)-1-methyl-5-(o-trifluoromethyl-phenyl)-1H-1,2,4-triazole, m.p. 109.5°-112° C.;

Quellen und Nachweise

ORD-Eintrag
ord-3daaab40184244b4bb87d50d9da2fd6c
Quelldatensatz
uspto-grants-1988_11
Patentnummer
US04788210

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