HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Acetic Anhydride → 3-Hydroxy-3'-(trifluoromethyl)acrylophenone acetate
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Acetic Anhydride | HCID 7918 | — |
| Edukt | 1,4-Dioxane | HCID 31275 | — |
| Edukt | 3-Hydroxy-3'-(trifluoromethyl)acrylophenone sodium salt | HCID 70590370 | — |
| Lösungsmittel | Water | HCID 962 | — |
| Produkt | 3-Hydroxy-3'-(trifluoromethyl)acrylophenone acetate | HCID 70477828 | — |
Reaktionsschritte
A suspension of 12.0 g. of 3-hydroxy-3'-(trifluoromethyl)acrylophenone sodium salt in 75 ml. of dioxane and 10 ml. of acetic anhydride is stirred at room temperature for 2 hours and then poured into water. The precipitate is collected by filtration, dissolved in methylene chloride and then passed through a hydrous magnesium silicate column as described in Example 1, giving the desired product, m.p. 55°-5° C.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US04236005 |
| Quelldatensatz | uspto-grants-1980_11 |
| ORD ID | ord-ce7f085a7a9b4a418043979685cee370 |
| Quellennotiz | uspto-grants-1980_11 |