HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
3-Dimethylamino-3'-trifluoromethylacrylophenone → 7-[3-(Trifluoromethyl)phenyl]pyrazolo[1,5-a]pyrimidine-3-carboxylic acid ethyl ester
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 3-Dimethylamino-3'-trifluoromethylacrylophenone | HCID 730024 | — |
| Edukt | HCID 178469928 | HCID 178469928 | — |
| Lösungsmittel | Acetic Acid | HCID 176 | — |
| Produkt | 7-[3-(Trifluoromethyl)phenyl]pyrazolo[1,5-a]pyrimidine-3-carboxylic acid ethyl ester | HCID 11198437 | — |
Reaktionsschritte
A mixture of 5.0 g. of 3-amino-4-carbethoxypyrazole and 7.84 g. of 3-dimethylamino-3'-(trifluoromethyl)acrylophenone in 25 ml. of glacial acetic acid is refluxed for 6 hours and then evaporated in vacuo to an oil. This oil is treated as described in Example 1, giving the desired product, m.p. 97°-99° C.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US04236005 |
| Quelldatensatz | uspto-grants-1980_11 |
| ORD ID | ord-f3e7d24f0dc44fdfbf25a2df623d7cf4 |
| Quellennotiz | uspto-grants-1980_11 |