HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Acetic Acid → 3-Cyano-7-(alpha,alpha,alpha-trifluoro-m-tolyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Acetic Acid | HCID 176 | — |
| Edukt | 3-amino-1H-pyrazole-4,5-dicarbonitrile | HCID 338830 | — |
| Edukt | 3-Dimethylamino-3'-trifluoromethylacrylophenone | HCID 730024 | — |
| Produkt | 3-Cyano-7-(alpha,alpha,alpha-trifluoro-m-tolyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide | HCID 23329828 | — |
Reaktionsschritte
A mixture of 4.86 g. of 3-dimethylamino-3'-(trifluoromethyl)acrylophenone, 50 ml. of glacial acetic acid and 2.66 g. of 3-aminopyrazole-4,5-dicarbonitrile is refluxed for 16 hours and then evaporated. The residue is treated as described in Example 1, giving the desired product, m.p. 236°-238° C.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US04236005 |
| Quelldatensatz | uspto-grants-1980_11 |
| ORD ID | ord-f5eba1b42ce04ea5959a8cdf8ef93231 |
| Quellennotiz | uspto-grants-1980_11 |