HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
1H-Indazole-5,6-diamine → 6-thienyl-1H-pyrazolo[3,4-g]quinoxaline
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 1H-Indazole-5,6-diamine | HCID 81900 | — |
| Edukt | Oxo(thiophen-2-yl)acetaldehyde | HCID 5272214 | — |
| Produkt | 6-thienyl-1H-pyrazolo[3,4-g]quinoxaline | HCID 18999799 | — |
| Produkt | 7-thienyl-1H-pyrazolo[3,4-g]quinoxaline | HCID 18999807 | — |
Reaktionsschritte
Condensation as shown in Step A of 5,6-diaminoindazole with a glyoxyloylthiophene in the presence of absolute alcohol results in ring formation of a mixture of 6-thienyl-1H-pyrazolo[3,4-g]quinoxaline and 7-thienyl-1H-pyrazolo[3,4-g]quinoxaline. These positional isomers can be separated by standard procedures, such as column chromatography.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US05476851 |
| Quelldatensatz | uspto-grants-1995_12 |
| ORD ID | ord-ff16d6430b4b4a79a0159c115bd9bafd |
| Quellennotiz | uspto-grants-1995_12 |