HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
2-Aminothiazole → 3-Cyclopentylmethoxy-4-nitrotoluene
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 2-Aminothiazole | HCID 2155 | — |
| Edukt | Benzene, 2-fluoro-4-methyl-1-nitro- | HCID 67966 | — |
| Edukt | Cyclopentanemethanol | HCID 77195 | — |
| Edukt | 2-(Cyclopentylmethoxy)-4-methylaniline | HCID 26189518 | — |
| Produkt | 1-(2-Cyclopentylmethoxy-4-methyl-phenyl)-3-thiazol-2-yl-urea | HCID 59732830 | 68% |
| Produkt | 3-Cyclopentylmethoxy-4-nitrotoluene | HCID 66998981 | 70% |
Reaktionsschritte
3-Cyclopentylmethoxy-4-nitrotoluene (0.82 g, 70%) was prepared from cyclopentylmethanol and 3-fluoro-4-nitrotoluene (0.77 g, 5.0 mmol) following the general procedure G. This was reduced to 2-cyclopentylmethoxy-4-methyl-aniline (0.58 g, 81%) following general procedure C. 1-(2-Cyclopentylmethoxy-4-methyl-phenyl)-3-thiazol-2-yl-urea (225 mg, 68%) was prepared from 2-cyclopentylmethoxy-4-methyl-aniline (205 mg, 1.0 mmol) and 2-aminothiazole (100 mg, 1.0 mmol) following the general procedure D.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | USRE045670E1 |
| Quelldatensatz | uspto-grants-2015_09 |
| ORD ID | ord-6f24db5e778d45d59328715bb04d5ca6 |
| Quellennotiz | uspto-grants-2015_09 |