HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
1-Bromo-3-chloropropane → 4-Chlorobenzyl-4-(3-chloropropyl)piperazine dihydrochloride
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 1-Bromo-3-chloropropane | HCID 8006 | — |
| Edukt | Potassium Hydroxide | HCID 14797 | — |
| Edukt | 4-Chlorobenzylpiperazine | HCID 134826 | — |
| Lösungsmittel | Dimethyl Sulfoxide | HCID 679 | — |
| Produkt | 4-Chlorobenzyl-4-(3-chloropropyl)piperazine dihydrochloride | HCID 20153189 | 74% |
Reaktionsschritte
Utilizing the procedure described in Example 1(a), 20.0 g of 1-(4-chlorobenzyl)piperazine, 100 ml of dimethyl sulfoxide, 15.0 g of potassium hydroxide and 15.0 of 1-bromo-3-chloropropane yielded 25.1 g (74% of theory) of 1-(4-chlorobenzyl)-4-(3-chloropropyl) piperazine dihydrochloride as a white crystalline solid.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US04618677 |
| Quelldatensatz | uspto-grants-1986_10 |
| ORD ID | ord-e07b1f5a44634c8bb736edcc776761d9 |
| Quellennotiz | uspto-grants-1986_10 |