HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Methanol → Ethyl 2-isopropylthiazole-5-carboxylate
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Methanol | HCID 887 | — |
| Edukt | Hexane | HCID 8058 | — |
| Edukt | Ethyl Acetate | HCID 8857 | — |
| Edukt | 2-Methylpropanethioamide | HCID 10909507 | — |
| Lösungsmittel | Chloroform | HCID 6212 | — |
| Produkt | Ethyl 2-isopropylthiazole-5-carboxylate | HCID 10608068 | 83% |
Reaktionsschritte
Using the procedure of Example 1J but replacing thioformamide with 2-methylpropane-thioamide provided, after silica gel chromatography using 9:1 ethyl acetate:hexane, the desired compound, Rf 0.8, (5% methanol in chloroform) in 83% yield.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US05597928 |
| Quelldatensatz | uspto-grants-1997_01 |
| ORD ID | ord-bf51796fa08a479293374d3939d3e627 |
| Quellennotiz | uspto-grants-1997_01 |