HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Thionyl Chloride → Ethyl 6-(chloromethyl)pyridine-2-carboxylate--hydrogen chloride (1/1)
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Thionyl Chloride | HCID 24386 | — |
| Edukt | 2-Pyridinecarboxylic acid, 6-(hydroxymethyl)-, ethyl ester | HCID 10921141 | — |
| Lösungsmittel | Dichloromethane | HCID 6344 | — |
| Produkt | Ethyl 6-(chloromethyl)pyridine-2-carboxylate--hydrogen chloride (1/1) | HCID 68457584 | — |
Reaktionsschritte
As for Reaction 1, using 45.14 g of ethyl 6-(hydroxymethyl)-2-pyridinecarboxylate and 33 g thionyl chloride in 500 ml dichloromethane. Yield 59.9 g
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07759369B2 |
| Quelldatensatz | uspto-grants-2010_07 |
| ORD ID | ord-183871bb9e68456ba638c22d39f17ad6 |
| Quellennotiz | uspto-grants-2010_07 |