HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
1-Aminopiperidin-4-OL → 5-Cyclohexyl-N-(4-hydroxypiperidin-1-yl)-6-(2,2,2-trifluoroethoxy)-3-pyridinecarboxamide
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 1-Aminopiperidin-4-OL | HCID 12125645 | — |
| Edukt | 5-Cyclohexyl-6-(2,2,2-trifluoroethoxy)nicotinic acid | HCID 71293952 | — |
| Produkt | 5-Cyclohexyl-N-(4-hydroxypiperidin-1-yl)-6-(2,2,2-trifluoroethoxy)-3-pyridinecarboxamide | HCID 71294089 | — |
Reaktionsschritte
The title compound was synthesized in analogy to Example 1 using 5-cyclohexyl-6-(2,2,2-trifluoro-ethoxy)-3-pyridinecarboxylic acid and 1-amino-4-piperidinol (CAN 79414-82-7) as starting materials; LC-MS (UV peak area/ESI) 96.4%, 402.1991 (M+H)+.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08648099B2 |
| Quelldatensatz | uspto-grants-2014_02 |
| ORD ID | ord-2eeb7b93cccc47458664bd6c7721f77c |
| Quellennotiz | uspto-grants-2014_02 |