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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 24311Erstellt: 24. Oktober 2026

Methylamine → N-methyl-2-oxoindoline-5-sulfonamide

https://huagongshe.com/de/reaction/24311

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
EduktMethylamineHCID 6329—
Edukt2-oxo-2,3-dihydro-1H-indole-5-sulfonyl chlorideHCID 4962506—
LösungsmittelTetrahydrofuranHCID 8028—
ProduktN-methyl-2-oxoindoline-5-sulfonamideHCID 1017690988%

Reaktionsschritte

A suspension of 3.38 g of 5-chlorosulfonyl-2-oxindole in 10 mL 2M methylamine in tetrahydrofuran was stirred at room temperature for 4 hours during which time a white solid formed. The precipitate was collected by vacuum filtration, washed twice with 5 mL of water and dried under vacuum at 40° C. overnight to give 3.0 g (88% yield) of 5-methylaminosulfonyl-2-oxindole.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS06855730B2
Quelldatensatzuspto-grants-2005_02
ORD IDord-fe9bd36b9da843ffb41b3aaadcf3b7a7
Quellennotizuspto-grants-2005_02