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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 24494Erstellt: 24. Oktober 2026

Piperidine → 3-(3-methyl-1H-indol-2-ylmethylene)-1,3-dihydroindole-2-one

https://huagongshe.com/de/reaction/24494

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
EduktPiperidineHCID 8082—
Edukt3-Methyl-1H-indole-2-carbaldehydeHCID 277260—
EduktOxindoleHCID 321710—
LösungsmittelEthanolHCID 702—
Produkt3-(3-methyl-1H-indol-2-ylmethylene)-1,3-dihydroindole-2-oneHCID 54160725—

Reaktionsschritte

A mixture of 2-oxindole (133 mg), 3-methylindole-2-carbaldehyde (190 mg) (prepared according to Synthetic Communications, 1986, 16, 1799) and piperidine (10 mg) in ethanol was held in a sealed tube at 95° C. for 4 hours. The mixture was cooled to room temperature. The solid was collected by vacuum filtration, washed with cold ethanol and dried in a vacuum oven to give 3-(3-methyl-1H-indol-2-ylmethylene)-1,3-dihydroindole-2-one.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS06855730B2
Quelldatensatzuspto-grants-2005_02
ORD IDord-d008e4a25a0f41618e2f339428d329a6
Quellennotizuspto-grants-2005_02