Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|
| Edukt | Phenacyl bromide | HCID 6259 | — |
| Edukt | 4-Amino-pyrido[2,3-e]pyrimidin-2-one | HCID 19366879 | — |
| Lösungsmittel | Dimethylformamide | HCID 6228 | — |
| Produkt | HCID 135418313 | HCID 135418313 | — |
Reaktionsschritte
A mixture of 4-Amino-pyrido[2,3-e]pyrimidin-2-one (95 mg) and αbromo-acetophenone (117 mg) in 4 mL of dimethylformamide (DMF) was heated at about 150° C. for 20 min. The reaction mixture was concentrated in vacuo and the residue was subjected to flash chromatography on silica gel with 10% methanol/methylene chloride as the eluent to afford 2-Phenylimidazo[1,2-c]pyrido[2,3-e]pyrimidin-5(6H)-one, (Compound 15), m.p. 329°-330° C.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patentnummer | US05212310 |
|---|
| Quelldatensatz | uspto-grants-1993_05 |
|---|
| ORD ID | ord-320e1807743244cdbe57665e69f96157 |
|---|
| Quellennotiz | uspto-grants-1993_05 |
|---|
