HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Glutaric anhydride → Succinimide glutarate
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Glutaric anhydride | HCID 7940 | — |
| Edukt | Dicyclohexylcarbodiimide | HCID 10868 | — |
| Edukt | N-Hydroxysuccinimide | HCID 80170 | — |
| Edukt | Glutarate(2-) | HCID 4418048 | — |
| Produkt | Succinimide glutarate | HCID 86592295 | — |
Reaktionsschritte
As depicted in above Scheme 2, 6-arm PEG (1) synthesized in the Scheme 1 is reacted with glutarate reagents, e.g., glutaric anhydride to synthesize 6-arm PEG-glutatic acid (6-arm PEG-GA) (2). The compound (2) was reacted with N-hydroxy succinimide (NHS) and N, N′-dicyclohexylcarbodiimide (DCC) to produce 6-arm PEG-succinimide glutarate (6-arm PEG-SG) (3).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US06858736B2 |
| Quelldatensatz | uspto-grants-2005_02 |
| ORD ID | ord-21362a60159840c9abdcc13b32c63fc9 |
| Quellennotiz | uspto-grants-2005_02 |