HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Trifluoroacetic acid → Morpholin-2-ylmethyl trifluoroacetate
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Trifluoroacetic acid | HCID 6422 | — |
| Edukt | tert-Butyl 2-(hydroxymethyl)morpholine-4-carboxylate | HCID 5201202 | — |
| Lösungsmittel | Dichloromethane | HCID 6344 | — |
| Produkt | Morpholin-2-ylmethyl trifluoroacetate | HCID 11206644 | — |
Reaktionsschritte
Tert-Butyl 2-(hydroxymethyl)-4-morpholinecarboxylate (5.13 g, 23.61 mmol) was treated with CF3CO2H (20 mL) in CH2Cl2 (50 mL) at room temperature for 3 h. The volatiles were removed in vacuo to give the subtitled compound (7.6 g).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07449475B2 |
| Quelldatensatz | uspto-grants-2008_11 |
| ORD ID | ord-cd13a1f2c918407faf5b11bd981b00ae |
| Quellennotiz | uspto-grants-2008_11 |