HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Thioacetamide → 5-(2-Methyl-4-thiazolyl)-3-nitropyrocatechol hydrobromide
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Thioacetamide | HCID 2723949 | — |
| Edukt | 2-Bromo-1-(3,4-dihydroxy-5-nitro-phenyl)-ethanone | HCID 21845596 | — |
| Lösungsmittel | Ethanol | HCID 702 | — |
| Produkt | 5-(2-Methyl-4-thiazolyl)-3-nitropyrocatechol hydrobromide | HCID 21459102 | — |
Reaktionsschritte
A mixture of 3.12 g of 2-bromo-3',4'-dihydroxy-5'-nitroacetophenone and 849.3 mg of thioacetamide are heated to boiling under reflux for 18 hours in 40 ml of ethanol. After cooling, the crystals are filtered under suction and recrystallized from methanol/isopropanol. There is obtained 5-(2-methyl-4-thiazolyl)-3-nitropyrocatechol hydrobromide of m.p. 280°-282°.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US05389653 |
| Quelldatensatz | uspto-grants-1995_02 |
| ORD ID | ord-a5b3873195ae4150b60aefa9620af38f |
| Quellennotiz | uspto-grants-1995_02 |