HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Sodium hydride → HCID 66886384, Verbindung
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Sodium hydride | HCID 24758 | — |
| Edukt | 3-(4-Fluoro-phenyl)-5-methyl-[1,2,4]triazole | HCID 43166756 | — |
| Edukt | tert-butyl N-(4-chloro-2-methylbutan-2-yl)carbamate | HCID 57429079 | — |
| Katalysator | Tetrabutylammonium Iodide | HCID 67553 | — |
| Lösungsmittel | 2(1H)-Pyrimidinone, tetrahydro-1,3-dimethyl- | HCID 81646 | — |
| Produkt | HCID 66886384 | HCID 66886384 | — |
Reaktionsschritte
5.88 g (33 mmol) 3-(4-fluoro-phenyl)-5-methyl-[1,2,4]triazole are dissolved in 40 mL DMPU and reacted as described for intermediate product 1c) with 11.04 g (50 mmol) of tert-butyl (3-chloro-1,1-dimethyl-propyl)-carbamate, 1.59 g (40 mmol, 60%) sodium hydride and 2.21 g (6 mmol) tetrabutylammonium iodide.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07423036B2 |
| Quelldatensatz | uspto-grants-2008_09 |
| ORD ID | ord-d610d48a86384329b37fabd60551af09 |
| Quellennotiz | uspto-grants-2008_09 |