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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 29810Erstellt: 24. Oktober 2026

5-Methyl-3-(4-trifluoromethylphenyl)-1H-[1,2,4]triazole → Tert-butyl {1,1-dimethyl-3-[5-methyl-3-(4-trifluoromethyl-phenyl)-[1,2,4]triazol-1-yl]-propyl}-carbamate

https://huagongshe.com/de/reaction/29810

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
Edukt5-Methyl-3-(4-trifluoromethylphenyl)-1H-[1,2,4]triazoleHCID 23228261—
Edukttert-butyl N-(4-chloro-2-methylbutan-2-yl)carbamateHCID 57429079—
ProduktTert-butyl {1,1-dimethyl-3-[5-methyl-3-(4-trifluoromethyl-phenyl)-[1,2,4]triazol-1-yl]-propyl}-carbamateHCID 86607261—

Reaktionsschritte

The target compound is obtained analogously to the method described for intermediate product 1c) from 4.90 g (21.6 mmol) 5-methyl-3-(4-trifluoromethyl-phenyl)-1H-[1,2,4]triazol and 7.17 g (32.4 mmol) tert-butyl (3-chloro-1,1-dimethyl-propyl)-carbamate. White solid. Yield: 5.06 g (57%); mass spectroscopy [M+H]+=413.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS07423036B2
Quelldatensatzuspto-grants-2008_09
ORD IDord-f16bcecf67304ff280fcc11eb5d1c7d1
Quellennotizuspto-grants-2008_09