HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
[1-(Methylsulfonyl)piperidin-4-yl]amine trifluoroacetate → [2-Amino-6-(1-methanesulfonyl-piperidin-4-ylamino)-pyridin-3-yl]-(5-fluoro-2-methoxy-4-methyl-phenyl)-methanone
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | [1-(Methylsulfonyl)piperidin-4-yl]amine trifluoroacetate | HCID 11975076 | — |
| Edukt | (2-Amino-6-chloro-pyridin-3-yl)-(5-fluoro-2-methoxy-4-methyl-phenyl)-methanone | HCID 58590831 | — |
| Produkt | [2-Amino-6-(1-methanesulfonyl-piperidin-4-ylamino)-pyridin-3-yl]-(5-fluoro-2-methoxy-4-methyl-phenyl)-methanone | HCID 11669262 | — |
Reaktionsschritte
The title compound was prepared from (2-Amino-6-chloro-pyridin-3-yl)-(5-fluoro-2-methoxy-4-methyl-phenyl)-methanone (Example 43) and 1-methanesulfonyl-piperidin-4-ylamine (Step A, Example 6) using the procedure described in Step B. Example 6. HRMS, observed 437.1653, Calcd for (M+H)+: 437.1654.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07423051B2 |
| Quelldatensatz | uspto-grants-2008_09 |
| ORD ID | ord-563ca61d07894ce6b1c970640de235b0 |
| Quellennotiz | uspto-grants-2008_09 |