HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
2-(3-Fluorophenyl)-6-hydroxychroman-4-one → 2-(3-Fluorophenyl)chroman-4,6-diol
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 2-(3-Fluorophenyl)-6-hydroxychroman-4-one | HCID 17978465 | — |
| Edukt | 2-Phenylchroman-4,6-diol | HCID 17978631 | — |
| Produkt | 2-(3-Fluorophenyl)chroman-4,6-diol | HCID 17978638 | — |
Reaktionsschritte
2-(3-Fluorophenyl)chroman-4,6-diol was prepared as described for 2-phenylchroman-4,6-diol in Example 8(a) starting from 220 mg of 2-(3-fluorophenyl)-6-hydroxychroman-4-one. 1H NMR (400 MHz, d6-DMSO) δ: 8.85 (s, 1H), 7.45 (m, 1H), 7.30-7.25 (m, 2H), 7.15 (m, 1H), 6.88 (d, 1H, J 2.8 Hz), 6.62 (d, 1H, J 8.7 Hz), 6.55 (dd, 1H, J 8.7, 2.8 Hz), 5.44 (d, 1H, J 7.0 Hz), 5.15 (d, 1H, J 10.7 Hz), 4.86 (m, 1H), 2.29 (m, 1H), 1.86 (m, 1H).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07425568B2 |
| Quelldatensatz | uspto-grants-2008_09 |
| ORD ID | ord-8e4b945ab18b45059cbea9c173546070 |
| Quellennotiz | uspto-grants-2008_09 |