HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
1,3-Dichloroacetone → 4-Chloromethyl-2-(3,5-dimethoxyphenyl)oxazole
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 1,3-Dichloroacetone | HCID 10793 | — |
| Edukt | 3,5-Dimethoxybenzamide | HCID 72878 | — |
| Produkt | 4-Chloromethyl-2-(3,5-dimethoxyphenyl)oxazole | HCID 22009728 | 59% |
Reaktionsschritte
In substantially the same manner as in Reference Example 31, 3,5-dimethoxybenzamide was allowed to react with 1,3-dichloroacetone to give 4-chloromethyl-2-(3,5-dimethoxyphenyl)oxazole. The yield was 59%. Recrystallization from ethyl acetate-hexane gave colorless needles, mp 85-86° C.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US06211215B1 |
| Quelldatensatz | uspto-grants-2001_04 |
| ORD ID | ord-1e068f773ee24b4ebacd0233d74729f9 |
| Quellennotiz | uspto-grants-2001_04 |