HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
3-Pyridineacetic acid, hydrochloride (1:1) → N-[(3pyridyl)acetyl]-D,L-alanine iso-butyl ester
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 3-Pyridineacetic acid, hydrochloride (1:1) | HCID 2723724 | — |
| Edukt | 2-Methylpropyl 2-aminopropanoate hydrochloride | HCID 86200109 | — |
| Produkt | N-[(3pyridyl)acetyl]-D,L-alanine iso-butyl ester | HCID 22492127 | — |
Reaktionsschritte
Following General Procedure F′ and using 3-pyridylacetic acid hydrochloride (Aldrich) and D,L-alanine iso-butyl ester hydrochloride (from Example B′ above), the title compound was prepared as a solid having a melting point of 62°-64° C. The reaction was monitored by tlc on silica gel (Rf=0.48 10% methanol/dichloromethane) and purification was by silica gel chromatography.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US06211235B1 |
| Quelldatensatz | uspto-grants-2001_04 |
| ORD ID | ord-e6860779d4444903abb55a298db6490e |
| Quellennotiz | uspto-grants-2001_04 |