Methanol → 2-Butyl-1,3-diazaspiro[4.4]non-1-en-4-one

Beteiligte Stoffe

Reaktionsschritte

To 19.6 g (0,1 mol) of 1-cyano-1-n-pentanoylaminocyclopentane dissolved in 70 ml of methanol, 5 g of Varion AD resin was added the reaction mixture was heated under reflux conditions for 3 hours. After filtration and evaporation 16.5 g (71.7%) of title compound was obtained, assay by GC: 92%.

Herkunft & Nachweise