HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
2-Acetylbenzoic acid → 1-{2-(4-methyl-1(2H)-phthalazinon-2-yl)-4-pyridyl}-3-hydroxymethyl-6,7-diethoxynaphthalene
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 2-Acetylbenzoic acid | HCID 68474 | — |
| Edukt | 1-(2-Hydrazino-4-pyridyl)-3-hydroxymethyl-6,7-diethoxynaphthalene | HCID 22007332 | — |
| Lösungsmittel | Ethylene Glycol | HCID 174 | — |
| Produkt | 1-{2-(4-methyl-1(2H)-phthalazinon-2-yl)-4-pyridyl}-3-hydroxymethyl-6,7-diethoxynaphthalene | HCID 22007441 | 87,5% |
Reaktionsschritte
1-(2-Hydrazino-4-pyridyl)-3-hydroxymethyl-6,7-diethoxynaphthalene (177 mg), 1-carboxy-2-methylcarbonylbenzene (86 mg) and ethylene glycol (1 ml) are treated in the same manner as in Example 104-(3) to give 1-{2-(4-methyl-1(2H)-phthalazinon-2-yl)-4-pyridyl}-3-hydroxymethyl-6,7-diethoxynaphthalene (211 mg), which is listed in Table 14.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US06214996B1 |
| Quelldatensatz | uspto-grants-2001_04 |
| ORD ID | ord-2ef8657737a6492fac4ec11efdf6fe8d |
| Quellennotiz | uspto-grants-2001_04 |