HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Tetrabromophthalic anhydride → 2,3,4,5-Tetrabromo-6-[(4-chloro-3-isopropoxycarbonyl-phenyl)carbamoyl]benzoic acid
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Tetrabromophthalic anhydride | HCID 12443 | — |
| Edukt | Isopropyl 5-amino-2-chlorobenzoate | HCID 369590 | — |
| Lösungsmittel | Toluene | HCID 1140 | — |
| Produkt | 2,3,4,5-Tetrabromo-6-[(4-chloro-3-isopropoxycarbonyl-phenyl)carbamoyl]benzoic acid | HCID 507316 | 87% |
Reaktionsschritte
Tetrabromophthalic anhydride (7.03 g, 0.015 mole), 1-methylethyl 5-amino-2-chlorobenzoate (3.24 g, 0.015 mole) and toluene (about 150 ml) were heated almost to reflux over 30 minutes. The reaction mixture was cooled and filtered to give the title compound, m.p. 169°-171° C. (decomp.) (8.92 g, 87% yield).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US05268389 |
| Quelldatensatz | uspto-grants-1993_12 |
| ORD ID | ord-28d9383bf766479eb480eb2c911469f3 |
| Quellennotiz | uspto-grants-1993_12 |