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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 327088Erstellt: 24. Oktober 2026

Neopentylamine → N-cyano N'-(2,2-dimethylpropyl)-2-pyridinecarboximidamide

https://huagongshe.com/de/reaction/327088

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
EduktNeopentylamineHCID 79882—
Edukt2-Pyridinecarboximidic acid, N-cyano-, methyl esterHCID 10012189—
LösungsmittelMethanolHCID 887—
ProduktN-cyano N'-(2,2-dimethylpropyl)-2-pyridinecarboximidamideHCID 1973454394%

Reaktionsschritte

Methyl N-cyano-2-pyridinecarboximidate (0.50 g, 3.1 mmol) was dissolved in methanol (10 ml), 2,2-dimethylpropylamine (0.30 g, 3.4 mmol) was added, and the resulting mixture was stirred at room temperature for 30 minutes. After the reaction was completed, the reaction solution was concentrated under reduced pressure, and the residue thus obtained was crystallized from dichloromethane-diethyl ether to give the title compound (0.63 g, 2.9 mmol, yield: 94%) as colorless needles.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS05272164
Quelldatensatzuspto-grants-1993_12
ORD IDord-54fcd94988754977916ff5c504f1ffa1
Quellennotizuspto-grants-1993_12