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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 328551Erstellt: 23. Oktober 2026

Cytidine Diphosphate → 4-hydroxy-1-beta-D-ribofuranosyl-tetrahydro-2(1H)-pyrimidinone uridine 5'-diphosphate

https://huagongshe.com/de/reaction/328551

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
EduktCytidine DiphosphateHCID 6132—
EduktAmmonium HydroxideHCID 14923—
KatalysatorRhodiumHCID 23948—
Produkt4-hydroxy-1-beta-D-ribofuranosyl-tetrahydro-2(1H)-pyrimidinone uridine 5'-diphosphateHCID 86734645—

Reaktionsschritte

In the manner given in Example 2D, cytidine 5'-diphosphate was hydrogenated in dilute ammonium hydroxide in the presence of a rhodium on alumina catalyst, and the mixture separated with a Craig extractor to give 4-hydroxy-1-β-D-ribofuranosyl-tetrahydro-2(1H)-pyrimidinone uridine 5'-diphosphate and 1-β-D-ribofuranosyl-tetrahydro-2(1H)-pyrimidinone 5'-diphosphate.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS04017606
Quelldatensatzuspto-grants-1977_04
ORD IDord-f4a534c9938a426c81e57cbe69dbea59
Quellennotizuspto-grants-1977_04