HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
4-(4-Nitrophenyl)pyridine → 4-(Pyridin-4-yl)aniline
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 4-(4-Nitrophenyl)pyridine | HCID 259219 | — |
| Katalysator | Palladium | HCID 23938 | — |
| Lösungsmittel | Methanol | HCID 887 | — |
| Produkt | 4-(Pyridin-4-yl)aniline | HCID 1512654 | 90,5% |
Reaktionsschritte
A mixture of 4-(4-nitrophenyl)pyridine (274 mg, 1.37 mmol) and Pd—C(10%, 80 mg) in MeOH (10 mL) was hydrogenated under balloon H2 for 20 h. The mixture was then filtered through celite. The filtrate was concentrated in vacuo to give 4-(pyridin-4-yl)aniline as a solid (211 mg).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08877760B2 |
| Quelldatensatz | uspto-grants-2014_11 |
| ORD ID | ord-b136c50eebdc4587874f3fe657e9b211 |
| Quellennotiz | uspto-grants-2014_11 |