HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
1-(p-Tolyl)piperazine → 1-(Biphenyl-2-ylmethyl)-4-(4-methylphenyl)piperazine
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 1-(p-Tolyl)piperazine | HCID 83113 | — |
| Edukt | (1,1'-Biphenyl)-2-carboxaldehyde | HCID 121052 | — |
| Edukt | Sodium triacetoxyborohydride | HCID 5049666 | — |
| Edukt | 1-(Biphenyl-2-ylmethyl)-4-phenylpiperazine | HCID 71602523 | — |
| Produkt | 1-(Biphenyl-2-ylmethyl)-4-(4-methylphenyl)piperazine | HCID 71602640 | — |
Reaktionsschritte
70.4 mg of the target compound (0.21 mmol, 47.7%) was obtained using 1-(4-methylphenyl)piperazine (155 mg, 0.88 mmol), biphenyl-2-carbaldehyde (80 mg, 0.44 mmol) and NaBH(OAc)3 (284 mg, 1.32 mmol) according to the synthesis method of Compound 1.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08883796B2 |
| Quelldatensatz | uspto-grants-2014_11 |
| ORD ID | ord-74c1411df83e4358b2eac4d6c1f495e6 |
| Quellennotiz | uspto-grants-2014_11 |