HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
1-(2-Methoxyphenyl)piperazine → 1-(2'-Chlorobiphenyl-2-ylmethyl)-4-(2-methoxyphenyl)piperazine
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 1-(2-Methoxyphenyl)piperazine | HCID 1346 | — |
| Edukt | 2'-Chloro-[1,1'-biphenyl]-2-carbaldehyde | HCID 1392375 | — |
| Edukt | Sodium triacetoxyborohydride | HCID 5049666 | — |
| Edukt | 1-(Biphenyl-2-ylmethyl)-4-phenylpiperazine | HCID 71602523 | — |
| Produkt | 1-(2'-Chlorobiphenyl-2-ylmethyl)-4-(2-methoxyphenyl)piperazine | HCID 71602688 | — |
Reaktionsschritte
69 mg of the target compound (0.18 mmol, 21.7%) was obtained using 1-(2-methoxyphenyl)piperazine (311 mg, 1.62 mmol), 2′-chlorobiphenyl-2-carbaldehyde (175 mg, 0.81 mmol) and NaBH(OAc)3 (523 mg, 2.43 mmol) according to the synthesis method of Compound 1.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08883796B2 |
| Quelldatensatz | uspto-grants-2014_11 |
| ORD ID | ord-413b741224ef49df82953419bac9267d |
| Quellennotiz | uspto-grants-2014_11 |