HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
1-(3-Fluorophenyl)piperazine → 1-(Biphenyl-3-ylmethyl)-4-(3-fluorophenyl)piperazine
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 1-(3-Fluorophenyl)piperazine | HCID 77418 | — |
| Edukt | 3-Phenylbenzaldehyde | HCID 121053 | — |
| Edukt | Sodium triacetoxyborohydride | HCID 5049666 | — |
| Edukt | 1-(Biphenyl-2-ylmethyl)-4-phenylpiperazine | HCID 71602523 | — |
| Produkt | 1-(Biphenyl-3-ylmethyl)-4-(3-fluorophenyl)piperazine | HCID 71678347 | — |
Reaktionsschritte
113.2 mg of the target compound (0.33 mmol, 59.4%) was obtained using 1-(3-fluorophenyl)piperazine (198 mg, 1.10 mmol), biphenyl-3-carbaldehyde (100 mg, 0.55 mmol) and NaBH(OAc)3 (355 mg, 1.65 mmol) according to the synthesis method of Compound 1.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08883796B2 |
| Quelldatensatz | uspto-grants-2014_11 |
| ORD ID | ord-bab3e528829c4687b63bcbdff8c4b4b8 |
| Quellennotiz | uspto-grants-2014_11 |